Generic Name: Spectinomycin Sulfate

Molecular Formula: C14H26N2O11S

CAS Number: 64058-48-6

Introduction:

Spectinomycin sulfate is a broad-spectrum antibiotic with strong inhibitory effects on both gram-positive and gram-negative bacteria. It is effective against Staphylococcus aureus, Streptococcus hemolyticus, Pneumococcus, Proteus vulgaris, Klebsiella pneumoniae, Mycoplasma and certain other pathogens.

Mode of Action:

Spectinomycin sulfate works by binding to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis and leading to bacterial death.

Indications:

Spectinomycin sulfate is indicated for the treatment of infections caused by susceptible bacteria in animals. It is commonly used to treat respiratory infections, urinary tract infections, and other bacterial infections in livestock and poultry.

Dosage and Administration:

The recommended dosage of spectinomycin sulfate may vary depending on the severity of the infection, the species of animal, and the route of administration. It is typically administered by injection, either intramuscularly or subcutaneously. The dosage should be determined by a veterinarian and the treatment course should be completed as prescribed.

Contraindications and Precautions:

Spectinomycin sulfate is contraindicated in animals with a known hypersensitivity to the drug. It should not be used in horses, as it may cause severe diarrhea and colitis. Caution should be exercised when administering the drug to animals with renal or hepatic dysfunction, as the drug may accumulate in these organs and cause toxicity.

Storage:

Spectinomycin sulfate should be stored in a cool, dry place, away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent contamination and degradation. Spectinomycin sulfate should be kept out of reach of children and unauthorized personnel.

Conclusion:

Spectinomycin sulfate is a broad-spectrum antibiotic that is effective against a wide range of bacterial pathogens. It is commonly used to treat respiratory and urinary tract infections in livestock and poultry. As with all antibiotics, spectinomycin sulfate should be used judiciously and only when necessary, to prevent the development of antibiotic resistance.

Spectinomycin Sulfate Introduction

Spectinomycin Sulfate is a broad-spectrum antibiotic used in both human and veterinary medicine. Its generic name is Spectinomycin Sulfate, and its chemical formula is C14H26N2O11S, with a CAS number of 64058-48-6. Spectinomycin Sulfate is commonly used to treat infections caused by gram-positive and gram-negative bacteria, as well as some mycoplasmas and other microorganisms.

Spectinomycin Sulfate is a bacteriostatic antibiotic, meaning that it inhibits bacterial growth by interfering with protein synthesis. Specifically, Spectinomycin Sulfate binds to the 30S subunit of bacterial ribosomes, preventing the incorporation of amino acids into growing polypeptide chains. This ultimately leads to the inhibition of bacterial protein synthesis, which can lead to bacterial cell death or at least a decrease in bacterial growth.

Spectinomycin Sulfate is effective against a variety of gram-positive and gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria gonorrhoeae. It is also effective against some mycoplasmas, which are bacteria-like microorganisms that lack a cell wall.

In veterinary medicine, Spectinomycin Sulfate is commonly used to treat respiratory and urinary tract infections in livestock, including cattle, swine, and poultry. It can also be used to treat mastitis in dairy cattle. Spectinomycin Sulfate is generally well-tolerated by animals, with few side effects reported.

Spectinomycin Sulfate is available in various forms, including as an injection, a powder for reconstitution, or a premix for addition to animal feed. The recommended dose and route of administration will depend on the type and severity of the infection being treated, as well as the age and species of the animal.

Spectinomycin Sulfate is typically well-tolerated by patients, with few side effects reported. However, like all antibiotics, it can potentially cause adverse effects in some individuals. Common side effects of Spectinomycin Sulfate include diarrhea, nausea, and vomiting. Rarely, more serious side effects such as allergic reactions or anaphylaxis may occur.

In terms of safety and regulatory compliance, Spectinomycin Sulfate is subject to various quality standards and regulations, including those established by the Chinese Veterinary Pharmacopoeia, the European Pharmacopoeia, and the United States Pharmacopeia. To ensure optimal quality and safety, Spectinomycin Sulfate should be stored in a cool, dry place, protected from light and moisture.

Overall, Spectinomycin Sulfate is a widely used antibiotic with a broad spectrum of activity against various gram-positive and gram-negative bacteria, as well as some mycoplasmas and other microorganisms. It is a safe and effective treatment option for many types of infections in both humans and animals, and its availability in multiple forms allows for flexibility in dosing and administration.