ε-Polylysine Hydrochloride Supplier,Drug Carrier

ε-Polylysine hydrochloride is a homopolymer composed of 25-35 L-lysine residues linked by α-ε-amide bonds. It has good water solubility and thermal stability, and in the human body, it can be broken down into lysine, which is one of the essential amino acids. Therefore, ε-polylysine hydrochloride has excellent biocompatibility and is suitable for use as a drug carrier. Its potential as a drug delivery system is worth further exploration.

Ⅰ.Drug Carrier Functions

1. Enhancing Drug Efficacy:  

ε-Polylysine hydrochloride is rich in cations and exhibits strong electrostatic interactions with anionic drug molecules. This allows for stable binding with drugs, improving their solubility and stability. It can also act as a permeation enhancer, helping drugs better penetrate cell membranes, thus increasing drug absorption efficiency and bioavailability.

2. Reducing Drug Side Effects:  

By precisely controlling the structure and properties of ε-polylysine hydrochloride, targeted drug delivery can be achieved, reducing the accumulation of drugs in non-target tissues and thus minimizing side effects.

3. Improving Drug Formulations:  

ε-Polylysine hydrochloride can be used as an excipient in drug formulations, for preparing various drug forms such as tablets, capsules, and injections, meeting the needs of different patients.

Ⅱ. Application Prospects

1. Application in Cancer Treatment:  

ε-Polylysine hydrochloride can form stable complexes with anti-cancer drugs, enhancing their anti-cancer activity. By targeting drug delivery, it can precisely deliver drugs to tumor tissues, reducing damage to normal tissues.

2. Application in Gene Therapy:  

ε-Polylysine hydrochloride can be used as part of gene carriers, helping gene fragments stably enter cells, enabling targeted gene expression and regulation.

3. Other Applications:  

In addition to its use in cancer and gene therapies, ε-polylysine hydrochloride can serve as an antimicrobial agent, antioxidant, and other functional additives, playing an important role in fields such as pharmaceuticals and daily chemicals.

Although ε-polylysine hydrochloride has many advantages as a drug carrier, its research and application still face some challenges, such as how to precisely control its structure and properties to meet the delivery needs of different drugs; how to further enhance its targeted delivery capabilities and bioavailability; and how to reduce production costs and address challenges in large-scale application. With the ongoing development of nanotechnology, biotechnology, and materials science, further breakthroughs and advancements in the research and application of ε-polylysine hydrochloride as a drug carrier are expected.

ε-Polylysine hydrochloride has broad application prospects and potential as a drug carrier. Through in-depth research and continuous exploration, it can play an important role in the pharmaceutical field and make a significant contribution to human health.