ε-Polylysine Hydrochloride Application, Manufacturer Price

The process of producing and applying ε-polylysine hydrochloride involves multiple aspects. Below is a detailed exploration of this process:

I. Production

1. Raw Materials and Fermentation

Raw Materials: The primary raw material for the production of ε-polylysine hydrochloride is Streptomyces diastatochromogenes.

Fermentation: Through controlled fermentation, Streptomyces diastatochromogenes is cultivated to produce ε-polylysine.

2. Extraction and Purification

Extraction: The fermentation broth undergoes several steps including ion exchange resin adsorption, desorption, and purification to obtain high-purity ε-polylysine.

Conversion to Hydrochloride Form: Further processing converts ε-polylysine into its hydrochloride form, i.e., ε-polylysine hydrochloride.

3. Quality Control

Quality Testing: Strict quality testing is required for raw materials, intermediate products, and final products to ensure quality and safety.

Testing Parameters: These may include purity, content, heavy metals, and microbial limits.

II. Applications

1. Food Preservation and Antisepsis

Food Preservative: ε-Polylysine hydrochloride is widely used as a preservative in the food industry.

Food Types: It can be used for preserving fruits, vegetables, beans, edible fungi, rice and rice products, wheat flour and its products, miscellaneous grains, meat and meat products, seasonings, beverages, etc.

Antimicrobial Spectrum: It has a broad antimicrobial spectrum, effectively inhibiting and killing Gram-positive and Gram-negative bacteria, yeasts, molds, viruses, etc.

Combination Use: In food applications, ε-polylysine is often used in combination with other substances such as alcohol, organic acids, and glycerides to enhance preservation effects.

2. Cell Culture and Transfection

Cell Adhesion: In the biomedical field, ε-polylysine hydrochloride can be used for cell adhesion and anchorage in cell culture.

Transfection: It is also commonly used in cell transfection, forming complexes with DNA to achieve efficient gene transfection.

3. Drug Encapsulation and Controlled Release Systems

Drug Delivery: As a carrier for drug encapsulation and controlled release systems, ε-polylysine hydrochloride has unique cationic properties and hydrophilicity. It can form complexes with anionic drugs, increasing drug stability and controllability, making it widely applicable in drug delivery and therapy.

4. Biodegradable Materials

Biodegradability: ε-Polylysine hydrochloride is a biodegradable polymer that can gradually degrade in the body, releasing its constituent amino acids. This property makes it valuable in tissue engineering, biological repair, and regenerative medicine.

5. Surface Modification and Coatings

Surface Properties: Due to its good adhesion and hydrophilicity, ε-polylysine hydrochloride can be used to improve the performance of material surfaces. For example, it can serve as an antibacterial coating, component of cell scaffolds, and biosensors, enhancing the functionality and biocompatibility of materials.

From production to application, ε-polylysine hydrochloride demonstrates its wide-ranging uses and importance across various fields. Its unique properties make it valuable in food preservation, biomedicine, and material science, highlighting its significant application potential.