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ε-Polylysine Hydrochloride Supplier,Various Methods of Use

TIME:2024-08-12

ε-Polylysine hydrochloride is a homopolymer obtained by adsorption, desorption, and purification of controlled fermentation broth of Streptomyces albulus using ion exchange resin. It possesses broad-spectrum antibacterial properties, effectively inhibiting a wide range of microorganisms, including Gram-positive and Gram-negative bacteria, yeasts, and molds.

ε-Polylysine hydrochloride is highly water-soluble and remains effective in inhibiting bacteria under pH conditions ranging from 2 to 9. It is also heat-resistant, not decomposing even in high-temperature environments (e.g., 121°C for 30 minutes), making it suitable for use in products that undergo heat processing. Its synergistic mechanism with organic acids such as acetic acid, citric acid, and malic acid mainly lies in their combined antimicrobial and bactericidal effects. Typically, organic acids have natural antimicrobial properties and can inhibit the growth and reproduction of microorganisms by lowering the pH of the solution, thereby disrupting the cell walls and membranes of the microbes.

When ε-polylysine hydrochloride is used in conjunction with organic acids, they can produce a synergistic effect, significantly enhancing the inhibition and killing of microorganisms. Organic acids can lower the environmental pH, creating an even more unfavorable growth environment for microorganisms, while ε-polylysine hydrochloride further inhibits microbial growth through its unique antibacterial mechanism.

Using ε-polylysine hydrochloride or organic acids alone may be less effective against certain types of microorganisms, but when combined, they can compensate for each other's shortcomings, broadening the spectrum of inhibition, and affecting a wider range of microorganisms. In certain conditions, such as high temperatures or alkaline environments, the effectiveness of using ε-polylysine hydrochloride or organic acids alone may decrease, but when combined, they can stabilize each other's active components, thereby enhancing overall stability.

Due to this synergistic effect, using ε-polylysine hydrochloride together with organic acids can achieve the same antibacterial effect while reducing the amount of each used, thereby lowering usage costs.

In the field of food preservation and anti-corrosion, the combination of ε-polylysine hydrochloride with organic acids like acetic acid can significantly extend the shelf life of food and inhibit pathogenic microorganisms on the surface or within the food. In the pharmaceutical field, their combination can be used to create drug formulations with stronger antibacterial effects.

The synergistic mechanism between ε-polylysine hydrochloride and organic acids mainly enhances antibacterial effects, broadens the antimicrobial spectrum, improves stability, and reduces the required dosage. This synergistic mechanism gives both substances broader application prospects in fields such as food preservation and pharmaceuticals.

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