Nisin specifications

Nisin is a natural antimicrobial peptide produced by certain strains of the bacteria Lactococcus lactis.It is commonly used as a food preservative, particularly in dairy products.Nisin has antimicrobial properties, primarily against Gram-positive bacteria, and it is effective at inhibiting the growth of various spoilage and pathogenic microorganisms.

The specifications for nisin can vary based on regulatory requirements, applications, and manufacturers.Nisin is a polypeptide with a molecular weight of around 3,500 Da. It consists of 34 amino acid residues, including unusual amino acids such as lanthionine and methyllanthionine, which are formed by post-translational modifications.

Nisin preparations should have a high degree of purity to ensure its effectiveness and safety. Typically, nisin preparations for food use are expected to be at least 95-98% pure.

Nisin is measured in terms of its antimicrobial activity, usually expressed in International Units (IU) or equivalent units.The activity is determined by its ability to inhibit the growth of a standardized test organism, often Lactococcus lactis or other relevant strains.

Nisin is soluble in water, and its solubility characteristics may be specified for various applications. The solubility can be affected by factors such as pH and temperature.

Nisin is commonly available in powder or liquid form. The color, odor, and taste may vary slightly depending on the source and production process.

Nisin should be stored under specified conditions to maintain its stability and activity. Typical storage conditions include cool, dry places, and protection from light.

Nisin used in food products must comply with regulations set by relevant authorities, such as the U.S. Food and Drug Administration (FDA) or the European Food Safety Authority (EFSA). Regulatory requirements may specify maximum levels of nisin allowed in different food products.

These specifications may vary among suppliers and regions, and it's crucial to refer to the specific product documentation provided by the manufacturer for precise information.