Nisin Long-term Cooperation,Control the Dosage

Nisin is a polypeptide substance produced by Lactococcus lactis, composed of 34 amino acid residues with a molecular weight of approximately 3500 Da. It effectively inhibits many Gram-positive bacteria that cause food spoilage, such as lactobacilli, streptococci, micrococci, staphylococci, and Listeria. Notably, it has a strong inhibitory effect on spore-forming bacteria like Bacillus and Clostridium, helping reduce the number of harmful bacteria in the gut, thus maintaining the balance of the intestinal microbiota.

Nisin can also promote the proliferation of beneficial bacteria, such as bifidobacteria and lactobacilli, which can synthesize essential vitamins for human growth and development, such as B vitamins and vitamin K, as well as essential amino acids like phenylalanine, valine, and threonine. These nutrients play an important role in human health.

Nisin can stimulate gastric juice secretion, increase gastrointestinal motility, and promote the digestion and absorption of food, helping to alleviate symptoms such as bloating and belching caused by indigestion. By enhancing the activity of immune cells and promoting the secretion of immune factors such as interleukin-2, nisin can boost the body's resistance to pathogens, thereby positively impacting gut health.

While nisin has many positive effects on gut microbiota, excessive intake or improper use in certain situations may lead to potential risks, such as gut microbiota imbalance and allergic reactions. Long-term excessive intake may disrupt the balance of the intestinal microecology, possibly reducing the number of beneficial bacteria and allowing harmful bacteria to proliferate, which could lead to issues like diarrhea and constipation. Some individuals may have allergic reactions to nisin, experiencing symptoms such as itching, redness, difficulty breathing, and in severe cases, potentially life-threatening reactions. Therefore, individuals known to be allergic to this component should avoid foods containing it.

Under normal usage, nisin has a positive regulatory effect on gut microbiota, helping to maintain the balance of the intestinal microecology, improve digestive function, and enhance immunity. However, excessive intake or improper use may pose potential hazards. Therefore, it is important to follow medical advice or the recommended dosage on product instructions and avoid excessive intake. Individuals known to be allergic to nisin should avoid related foods or products.