Brand Name: Shengxue Qingkang
Generic Name: Colistin Sulfate Premix
Main Ingredients: Colistin
Description: This product is a white to yellowish granule or powder.
Specifications: 100g: 10g (300 million units); 100g: 20g (600 million units)
Pharmacological Action:
Colistin is a polypeptide and alkaline cationic surfactant that works by interacting with phospholipids inside bacterial cell membranes, penetrating the membrane and disrupting its structure, leading to changes in membrane permeability and bacterial death, thus producing bactericidal effects. This product has strong antibacterial effects against Gram-negative bacteria such as aerobic bacteria, Escherichia coli, hemophilus, Klebsiella, Pseudomonas aeruginosa, Salmonella, and Shigella.
Indications: This polypeptide antibiotic is mainly used to treat intestinal infections caused by Gram-negative bacteria.
Introduction to Colistin Sulfate Premix
Colistin sulfate premix is a medication used in veterinary medicine to treat bacterial infections in livestock. The medication is effective against Gram-negative bacteria, including Escherichia coli and Salmonella species. It is available in a premix form that can be easily added to feed, making it a convenient and effective treatment option for large groups of animals.
Indications
Colistin sulfate premix is indicated for the treatment of bacterial infections in livestock, including:
Enteritis caused by E. coli and Salmonella species
Respiratory infections caused by Pasteurella multocida and other bacteria
Other bacterial infections, such as metritis and septicemia
Dosage and Administration
The recommended dosage of colistin sulfate premix is 50-100 mg/kg body weight per day for a period of 3-5 days. The medication should be mixed into the animal feed at a rate of 10-20 g of premix per 100 kg of body weight per day. The medicated feed should be the only source of feed during the treatment period.
Contraindications
Colistin sulfate premix should not be given to animals with a known hypersensitivity to colistin or any of the other ingredients in the medication. It should not be used in animals intended for human consumption.
Side Effects
The most common side effects of colistin sulfate premix include:
Diarrhea
Vomiting
Loss of appetite
Dehydration
In rare cases, the medication can cause an allergic reaction, which can be life-threatening. If an animal experiences an allergic reaction, immediate veterinary attention is required.
Precautions
Colistin sulfate premix should be handled with care and kept out of reach of children. It should be stored in a cool, dry place and protected from light. The medication should not be used past the expiration date printed on the packaging.
The medication should be used with caution in pregnant and lactating animals, as the safety of the medication in these animals has not been established.
Conclusion
Colistin sulfate premix is an effective medication for the treatment of bacterial infections in livestock. Its ease of administration and broad-spectrum activity make it a valuable tool in the management of bacterial infections. However, as with any medication, it should be used with caution and only under the guidance of a veterinarian.