The Nisin manufacturer suggests its storage method

The Nisin manufacturer suggests its storage method

Nisin, also known as nisin streptococcus lactis, is a natural preservative. To ensure its quality and activity, manufacturers typically recommend the following storage methods:

I. Environmental Conditions

Temperature

Nisin should be stored in a low-temperature environment, with a recommended storage temperature of 2–8°C. Within this range, microbial growth and reproduction are effectively inhibited, and the degradation rate of Nisin is slowed, thereby maintaining its activity and stability. For example, in experimental studies, Nisin was stored at room temperature (25°C), 4°C, and -20°C. After a period, the activity of Nisin stored at room temperature decreased significantly, while those stored at 4°C and -20°C remained relatively stable. Among them, storage at 4°C showed better results, maintaining high activity over a long period.

Humidity

The relative humidity of the storage environment should be kept low, generally recommended to be no more than 60%. High humidity can cause Nisin to absorb moisture, potentially leading to caking, deterioration, and other issues. Therefore, the storage area should be kept dry, and dehumidification equipment can be used to regulate humidity.

Light

Nisin should be protected from direct sunlight and stored in a cool, dark place. Light may trigger photochemical reactions in Nisin, causing changes in its structure and activity. For this reason, it is usually stored in brown bottles or opaque containers and placed in cool corners of warehouses.

II. Packaging Requirements

Sealing

Ensure that the packaging of Nisin has good airtightness to prevent the entry of air, moisture, and other contaminants. If the packaging is not tightly sealed, Nisin can easily come into contact with oxygen and moisture in the air, accelerating its oxidation and deterioration. For example, aluminum foil composite bags or sealed cans can be used for packaging, and it is essential to ensure that the packaging is not damaged during storage and transportation.

Packaging Materials

Select appropriate packaging materials with good chemical stability and barrier properties, which should not react chemically with Nisin or affect its quality. Common packaging materials include plastic films such as polyethylene and polypropylene, as well as aluminum foil.

III. Storage Period and Monitoring

Storage Period

Manufacturers generally specify the recommended storage period for Nisin in the product manual, which is typically 1–2 years under suitable storage conditions. However, the actual storage period may vary depending on storage conditions, so regular quality inspections of the product are necessary.

Quality Monitoring

During storage, it is recommended to regularly monitor the quality of Nisin, including activity testing and microbial testing. If significant decreases in Nisin activity or issues such as microbial contamination are detected, timely measures should be taken, such as replacing packaging, adjusting storage conditions, or discontinuing use.